Fig. S1.
CotH proteins share sequence similarity with protein kinases. CLANS clustering analysis is represented graphically as the network of BLAST-derived sequence similarities (edges) between representatives of known kinase families (dots). All PKL clan families are included, including those clan families predicted to have a PKL fold, such as the Fam69 family. Magenta, CotH; red, Fam20; pink, Fam198; brown, HipA; dark blue, PI3_PI4K; light green, actin-fragmin kinases; light blue, CotS; cyan, Fam69; yellow, pkinase (typical eukaryotic Ser/Thr and Tyr kinases).
