IBB PAS Repository

Bacteriophages as Factories for Eu2O3 Nanoparticle Synthesis

Golec, Piotr and Żelechowska, Kamila and Karczewska-Golec, Joanna and Karczewski, Jakub and Leśniewski, Adam and Łoś, Marcin and Węgrzyn, Grzegorz and Kłonkowski, Andrzej M. (2017) Bacteriophages as Factories for Eu2O3 Nanoparticle Synthesis. Bioconjugate Chemistry, 28 (7). pp. 1834-1841. ISSN 1520-4812

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The use of phage display to identify peptides with an ability to bind and synthesize Eu2O3 nanoparticles is demonstrated in this report. This is the first report of modified phages specifically binding a lanthanide. The peptides exposed on virions revealed very strong binding to Eu2O3 nanoparticles and the ability to catalyze Eu2O3 nanoparticles' formation from Eu(OH)3 and Eu(NO3)3 solutions. The luminescence emission spectrum of Eu3+ ions indicated that these ions existed mostly in sites deviated from the inversion symmetry in crystalline Eu2O3 aggregates and gelatinous Eu(OH)3 precipitate. The ability of phage-displayed peptides to catalyze formation of Eu2O3 nanoparticles provides a useful tool for a low-cost and effective synthesis of lanthanide nanoparticles, which serve as attractive biomedical sensors or fluorescent labels, among their other applications.

Item Type:Article
Subjects:Q Science > Q Science (General)
Q Science > QD Chemistry
Q Science > QH Natural history > QH301 Biology
Q Science > QH Natural history > QH426 Genetics
Q Science > QR Microbiology
Q Science > QR Microbiology > QR355 Virology
Divisions:Laboratory of Molecular Biology (in Gdansk)
ID Code:1358
Deposited By: PhD Piotr Golec
Deposited On:27 Jun 2017 07:12
Last Modified:08 Jan 2018 12:12

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