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5-Methyl-3,8-di-(2-amino-4-bromophenyl)-4,9-dioxa-1,2,6,7-tetraaza-5λ5-phosphaspiro[4.4]nona-2,7-diene

Kasperowicz, Sławomir and Czerwińska, Jolanta and Majchrzak, Bartosz and Tudek, Barbara and Mieczkowski, Adam (2018) 5-Methyl-3,8-di-(2-amino-4-bromophenyl)-4,9-dioxa-1,2,6,7-tetraaza-5λ5-phosphaspiro[4.4]nona-2,7-diene. Molbank, 2017 (1). M978. ISSN 1422-8599

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Official URL: http://www.mdpi.com/1422-8599/2018/1/M978

Abstract

5-Methyl-3,8-di-(2-amino-4-bromophenyl)-4,9-dioxa-1,2,6,7-tetraaza-5λ5-phosphaspiro[4.4]nona-2,7-diene was obtained by condensation of 2-amino-5-bromobenzohydrazide and methylphosphonyl dichloride in the presence of triethylamine. An initial biological screening was performed for the resulting product. The synthesized compound showed relatively strong cytotoxic activity, which was, however, similar for cancer and non-cancer cell lines

Item Type:Article
Subjects:Q Science > QD Chemistry
R Medicine > RM Therapeutics. Pharmacology
Divisions:Department of Biophysics
ID Code:1496
Deposited By: Dr Adam Mieczkowski
Deposited On:31 Jan 2018 12:46
Last Modified:31 Jan 2018 12:46

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