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Hierarchical binding of copperII to N-truncated Ab4–16 peptide

Teng, Xiangyu and Stefaniak, Ewelina and Girvan, Paul and Kotuniak, Radosław and Płonka, Dawid and Bal, Wojciech and Ying, Liming (2020) Hierarchical binding of copperII to N-truncated Ab4–16 peptide. Metallomics, 12 . pp. 470-473. ISSN 1756-591X

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Abstract

N-Truncated Ab4–42 displays a high binding affinity with CuII. A mechanistic scheme of the interactions between Ab4–42 and CuII has been proposed using a fluorescence approach. The timescales of different conversion steps were determined. This kinetic mechanism indicates the potential synaptic functions of Ab4–42 during neurotransmission.

Item Type:Article
Subjects:Q Science > QD Chemistry
Q Science > QP Physiology
Divisions:Department of Biophysics
ID Code:1906
Deposited By: Mr Dawid Płonka
Deposited On:06 Aug 2020 07:40
Last Modified:06 Aug 2020 07:40

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