Gawel, Damian and Jonczyk, Piotr and Fijalkowska, Iwona J. and Schaaper, Roel (2011) dnaX36 mutator of Escherichia coli: effects of the tau subunit of the DNA polymerase III holoenzyme on chromosomal DNA replication fidelity. Journal of Bacteriology, 193 (1). pp. 296-300.
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Abstract
The Escherichia coli dnaX36 mutant displays a mutator effect, reflecting a fidelity function of the dnaX-encoded τ subunit of the DNA polymerase III (Pol III) holoenzyme. We have shown that this fidelity function (i) applies to both leading- and lagging-strand synthesis, (ii) is independent of Pol IV, and (iii) is limited by Pol II.
| Item Type: | Article |
|---|---|
| Subjects: | Q Science > Q Science (General) |
| Divisions: | Laboratory of Mutagenesis and DNA Repair |
| ID Code: | 213 |
| Deposited By: | Piotr Jonczyk |
| Deposited On: | 21 Feb 2012 09:19 |
| Last Modified: | 14 Oct 2014 10:13 |
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