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Recombinant Cytokines from Plants

Sirko, Agnieszka and Vanek, Tomas and Góra-Sochacka, Anna and Redkiewicz, Patrycja (2011) Recombinant Cytokines from Plants. International Journal of Molecular Sciences, 12 (6). pp. 3536-3552. ISSN 1422-0067

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Official URL: http://www.mdpi.com/journal/ijms


Plant-based platforms have been successfully applied for the last two decades for the efficient production of pharmaceutical proteins. The number of commercialized products biomanufactured in plants is, however, rather discouraging. Cytokines are small glycosylated polypeptides used in the treatment of cancer, immune disorders and various other related diseases. Because the clinical use of cytokines is limited by high production costs they are good candidates for plant-made pharmaceuticals. Several research groups explored the possibilities of cost-effective production of animal cytokines in plant systems. This review summarizes recent advances in this field.

Item Type:Article
Subjects:S Agriculture > SB Plant culture
ID Code:228
Deposited By: dr Anna Gora-Sochacka
Deposited On:15 Mar 2012 08:15
Last Modified:28 Mar 2012 20:36

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