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LCRAnnotationsDB: a database of low complexity regions functional and structural annotations

Ziemska-Legiecka, Joanna and Jarnot, Patryk and Szymańska, Sylwia and Błaszczyk, Dagmara and Staśczak, Alicja and Langer-Macioł, Hanna and Lucińska, Kinga and Widzisz, Karolina and Janas, Aleksandra and Słowik, Hanna and Śliwińska, Wiktoria and Gruca, Aleksandra and Grynberg, Marcin (2024) LCRAnnotationsDB: a database of low complexity regions functional and structural annotations. BMC Genomics, 25 (1251). ISSN 1471-2164

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Abstract

Low Complexity Regions (LCRs) are segments of proteins with a low diversity of amino acid composition. These regions play important roles in proteins. However, annotations describing these functions are dispersed across databases and scientific literature. LCRAnnotationsDB aims to consolidate knowledge about LCRs and store relevant annotations in a single place. To unify redundant annotations, we assigned them categories based on similarity in function, protein structure, and biological process. Categories are organized hierarchically by linking them to Gene Ontology terms. The LCRAnnotationsDB database can be accessed at https://lcrannotdb.lcr-lab.org/.

Item Type:Article
Subjects:Q Science > Q Science (General)
ID Code:2502
Deposited By: Marcin Grynberg
Deposited On:10 Jan 2025 08:12
Last Modified:10 Jan 2025 08:12

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