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DNAtraffic—a new database for systems biology of DNA dynamics during the cell life

Table 1.

Distribution of the orthology classes into DNA maintenance network in DNAtraffic database

General name of super-pathway Name of process Number of orthology class
Genome dynamics Chromatin remodeling 72
Histones 5
Histone modifications 75
Transcription 34
Transcription factors 35
Heterochromatin formation 27
Telomere maintenance 23
Prokaryotic nucleoid remodeling 12
DNA synthesis DNA replication 67
TLS 13
Rad6 pathway 5
DNA repair Direct repair
    Direct reversal 8
Single-strand breaks repair
    Base excision repair 39
    Nucleotide excision repair 47
    Mismatch repair 42
    Very short patch repair 1
Double-strand breaks repair
    Homologous recombination 56
    FA pathway 58
    NHEJ 17
Damage checkpoint DDR 23
Prokaryotic SOS response 18
Nucleotide level Modulation of nucleotide pools 6

This Article

  1. Nucleic Acids Res vol. 40 no. D1 D1235-D1240

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