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A highly sensitive electrochemical genosensor based on Co-porphyrin-labelled DNA.

Grabowska, Iwona and Singleton, Daniel G and Stachyra, Anna and Góra-Sochacka, Anna and Sirko, Agnieszka and Zagórski-Ostoja, Włodzimierz and Radecka, Hanna and Stulz, Eugen and Radecki, Jerzy (2014) A highly sensitive electrochemical genosensor based on Co-porphyrin-labelled DNA. Chemical communications (Cambridge, England), 50 (32). pp. 4196-9. ISSN 1364-548X

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Official URL: http://pubs.rsc.org/en/content/articlepdf/2014/cc/...

Abstract

We report the use of Co-porphyrins as electrochemical tags for a highly sensitive and selective genosensor. An avian influenza virus-based DNA sequence characteristic of H5N1 was detected at femtomolar levels from competing non-complementary sequences through hybridisation with the labeled DNA.

Item Type:Article
Subjects:Q Science > QD Chemistry
T Technology > TP Chemical technology
ID Code:763
Deposited By: dr Anna Gora-Sochacka
Deposited On:31 Oct 2014 08:55
Last Modified:31 Oct 2014 08:55

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